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Dalton Medicinal Chemistry

Built on the strength and experience of 25 years of Dalton Pharma Services excellence, Dalton Medicinal Chemistry is a highly focused team of committed, knowledgeable medicinal chemists with expertise in small molecule drug discovery and development from Big Pharma and Biotech.

 

Dalton Medicinal Chemistry augments partners’ in-house expertise and capabilities, serving as an extension of their R&D. We work closely with our partners to design and synthesize compounds for their targets and assays, leading ultimately to the identification of development candidates.

Our track record of identifying novel chemical entities for our partners’ Discovery/Development pipelines has been demonstrated to-date through three publicly announced partnerships with Biotech (BioRelix & Bikam) and Pharma (Boehringer Ingelheim).

Focus
  • Quality and creativity
  • Commitmet to understanding and helping our partners achieve their goals
  • Timely, clear, detailed communication and coordination of key activities
  • Responsiveness to timelines and changing priorities; high flexibility
Expertise
  • Structure- and ligand-based analog design
  • Synthetic organic chemistry of all major chemotypes; focused library synthesis
  • Rapid, efficient execution of iterative design, synthesis and SAR elucidation
  • Understanding and experience in Drug Discovery of major target classes
  • Problem solving – synthetic Discovery, SAR analysis, ADMET issues
Dalton Medicinal Chemistry has strong experience in Fragment-to-Lead, Hit-to-Lead, and Lead Optimization in advancing compounds to development against a wide variety of target types from a host of therapeutic areas.

Selected Areas of Previous Experience
 
  • Antibacterials
  • Antivirals
  • Diabetes/obesity
  • Cancer/oncology
  • Neuropathic pain
  • Inflammation
  • Multiple Sclerosis
  • Alzheimer’s
  • Cardiovascular agents
  • Anti-aging
Contacts
  Judd Berman
Cofounder
Dalton Medicinal Chemistry
416-661-2102 x331
jberman@dalton.com
Peter Pekos
Founder and President
Dalton Pharma Services
416-661-2102
ppekos@dalton.com
 
Dalton Pharma Services is a Health Canada approved contract manufacturer that supplies chemistry, analytical and formulation development services to the biotechnology and pharmaceutical industries. Dalton provides cGMP manufacturing of solid dosage forms and aseptic filling services to its customers at any stage of the regulatory process (Phase I, II, III or commercial). The company produces active pharmaceutical ingredients at the gram or kilogram scale, and conducts sterile fills to produce batches of finished drug product in vials or syringes, either aseptically filled or terminally sterilized, under fully validated conditions.
 

 

 

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