Dalton Announces Addition of Flow Chemistry Technology
In Flow Chemistry, two or more reagents are continuously pumped into a small flow reactor, where they mix and then react under thermal control. Mixing is completed in a matter of seconds instead of the much longer timeframes characteristic of conventional reactors. The reaction temperature can be raised above the boiling point of the solvent very quickly, resulting in faster reactions. The high surface area to volume ratio in a small flow reactor allows for nearly instantaneous control over reaction temperatures, giving potentially cleaner products and increased reaction safety in all custom synthesis and process development projects. Scale-up issues are minimized through the more consistent control of mixing and heat transfer throughout the reaction at any scale, even up to a tonne. Flow Chemistry also allows a faster change-over between the different custom synthesis projects.
"Adding flow chemistry technology keeps us on the leading edge of the chemistry business, and builds on three decades of experience and innovation in custom chemical synthesis," noted Peter Pekos, CEO & President of Dalton Pharma Services. "Our clients need more efficient and scalable approaches to custom synthesis which enable safe cost management and environmental responsibility. By being able to seamlessly transfer the chemical process to our cGMP API manufacturing suites, clients can accelerate their drug development programs."
Dalton has initiated work with small scale reactions up to several hundred grams and will continue to expand the scale of our Flow Chemistry capabilities in API process development and custom synthesis to meet the needs of our clients. Please contact us for more information.
About Dalton:
Dalton Chemical Laboratories Inc. o/a Dalton Pharma Services is a Health Canada approved and FDA registered GMP contract service provider of integrated chemistry, drug development and manufacturing services to the pharmaceutical and biotechnology industries. We bring 30 years of experience to our client's projects and emphasize quality, speed and flexibility.
Dalton can accelerate your drug discovery and development program by integrating process development, API manufacturing and finish dose manufacturing all at a single location. Our full range of services in-house (drug discovery, flow chemistry, formulation and process development, custom synthesis, cGMP sterile fill/finish, cGMP API manufacturing and/or dosage form manufacturing) all at one location enables us to be adaptable, flexible and cost-effective. To learn more about Dalton visit https://www.dalton.com.
Our CMO 2016 Leadership Awards in the categories of Quality, Reliability, Capabilities, Expertise and Compatibility including “On-Time Delivery” and “Right First Time” from Life Science Leader reflect our ongoing commitment to our clients, peers and the business community.